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Guoqiang Gu, Ph.D., Associate
Professor
Research Specialty: Beta Cell Development, Function, and Survival
Research Description:
We investigate the cellular and molecular mechanisms underlying
islet cell differentiation and function, which include multiple
endocrine cell typesy. Our basic strategy is to first
unambiguously identify progenitors of each specific cell type, then
examine the molecular networks and cellular interactions for their
development and function. Our studies focus on the following areas:
1) Technology development, which allow us to identify pure
progenitor cells that give rise to specific functional
cells; 2) Exploration of novel mode of cell-cell
communicationthat utilize small molecules and GAP
junctions for coordinated cellular differentiation; 3)
Mechanisms underlying differentiation, survival, and function of
beta cells. We utilizes both mouse and chicken embryos as
models.
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Version 2.23
Released July 13, 2020