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Current and ongoing beta cell research is presented in this weekly seminar by faculty, postdoctoral fellows and students. If you are interested in attending the Beta Cell Interest Group (BIG) seminars and joining the BIG community, please contact David Jacobson.
|Start Date / Time||March 26, 2014 at 9:00 AM|
|End Date / Time||March 26, 2014 at 10:00 AM|
|Location||512 Light Hall|
|Presenter Name||Kristie Aamodt (Powers)|
|Presentation Title||Signals in the Islet Microenvironment Modulated by Vascular Endothelial Growth Factor A Promote Beta Cell Proliferation|
|Status||This meeting has already occurred|
Summary: Overexpressing vascular endothelial growth factor A (VEGF-A) in mature beta cells leads to endothelial cell expansion and beta cell loss followed by a transient, but robust increase in beta cell proliferation. This proliferation occurs in response to signals derived from the local islet microenvironment composed of endocrine cells, endothelial cells, and macrophages recruited to islets upon VEGF-A overexpression.
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Released July 13, 2020