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|Start Date / Time||May 15, 2013 at 9:00 AM|
|End Date / Time||May 15, 2013 at 10:00 AM|
|Location||512 Light Hall|
|Presenter Name||Brian McKenna (Stein lab)|
|Presentation Title||The identification and characterization of Pdx1 co-regulators|
|Status||This meeting has already occurred|
The transcription factor Pdx1 makes critical contributions to the identity and proliferative capacity of newly forming b-cells. Using the RE-CLIP co-immunoprecipitation technique coupled with mass spectrometry, we have identified a substantial number of novel Pdx1-interacting factors with a wide range of cellular functions. My presentation will focus on Pdx1s interaction with the Swi/Snf complex, which utilizes the energy generated from ATP-hydrolysis to mobilize histones and modulate transcription.