Current and ongoing beta cell research is presented in this weekly seminar by faculty, postdoctoral fellows and students. If you are interested in attending the Beta Cell Interest Group (BIG) seminars and joining the BIG community, please contact David Jacobson.

Record History
Added on October 4, 2012 at 3:10 PM by Brown, Deborah
Modified on April 4, 2013 at 9:21 AM by Brown, Deborah
Shared with (contributions)
Public: Beta Cell Interest Group (BIG) Weekly Seminar
BIG: Beta Cell Interest Group (BIG) Weekly Seminar Master

Meeting Details

Start Date / Time April 10, 2013 at 9:00 AM
End Date / Time April 10, 2013 at 10:00 AM
Duration 1 hour(s)
Location 512 Light Hall
Presenter Name Jing Liu (Gu lab)
Presentation Title Stochastic-like Activation of Myt1/Nkx2.2 in Subsets of Ngn3-Expressing Progenitors Facilitates Beta Cell Fate Choice in Pancreatic Development
Status This meeting has already occurred

Meeting Agenda/Notes


Ngn3+ progenitors give rise to all types of endocrine cells during pancreatic development. However, how endocrine cell fate choice is made remains unclear. Here, we use a bipartite Cre cell lineage tracing system to show that coexpression of Myt1/Nkx2.2 with Ngn3 biases Ngn3+ progenitors towards beta cell fate.