Common Name | RQH-SCN5A-SV129 |
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VCMR ID | YI |
Date Cryopreserved | 2018-04-10 |
Method of Cryopreservation | Sperm |
Trial IVF % Fertilization | 31.00% |
Mutation #1: Targeted Mutagenesis | |||
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Allele |
Name: sodium channel, voltage-gated, type V, alpha; targeted mutation, Dan M Roden Symbol: Scn5atm(R222Q))Rdn |
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Zygosity at cryopreservation | Heterozygous | ||
PCR Genotyping Protocol | Genotyping_Protocol_YI.pdf | ||
Citations |
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Strain Type | Congenic Strain |
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Chimera/Founder Genetic Background | 129S6/SvEvTac |
Cryopreservation Strain Background (VCMR) | 129S6/SvEvTac |
Viability and Fertility Data | Homozygous R222Q pups are viable, but are usually smaller than normal and do not live past 1 month of age. Most die before they are weaned. Many are probably eaten by the mother. |