Ken Lau, Ph.D.
Associate Professor of Cell and Developmental Biology
Associate Professor of Surgery



Keywords: VCSCB SPRING seminar

Record History
Added on August 11, 2021 at 3:59 PM by Uttz, Pam
Modified on October 27, 2021 at 9:53 AM by Uttz, Pam
Shared with (contributions)
Public: SPRING Meeting

Meeting Details

Start Date / Time November 3, 2021 at 9:00 AM
End Date / Time November 3, 2021 at 10:00 AM
Duration 1 hour(s)
Location Zoom
Presenter Name Ken Lau, Ph.D.
Presentation Title Cellular plasticity and stability in gut health and disease
Status This meeting has already occurred

Meeting Agenda/Notes

Membership Renewal talk

The Lau Lab’s research is interested in cellular plasticity of ileal and colonic epithelial cells upon differential exposure to an intact microenvironment (microbes/immune cells). Our lab uses sequencing-based -omics techniques and associated computational approaches to decipher the fate choices and functions of differentiated/differentiating/metastable cells in the gut. Here, we review our recent work on metaplastic transition of serrated polyps and its consequences on cytotoxic T cell interaction, and newer work on the consequences of manipulating Paneth cells in microbial-induced colitis. This talk will be focused on the value of experimental validation as opposed to tissue profiling and characterization. We will also emphasize our short- and medium-term future plans to further these studies. 


Document SPRING_Meeting_11.03.2021_Lau.pdf - Added on October 27, 2021 at 9:52 AM by Pam Uttz