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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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B6.Slc3a1em1/Vu
A C57Bl6/NHsd strain contains a knockout allele of Slc3a1. This animal was created to study cystinuria, a human disease involving kidney stones.
- Record History
- Added on December 18, 2020 at 10:08 AM by Skelton, Jennifer
Modified on December 18, 2020 at 10:18 AM by Skelton, Jennifer - Shared with (contributions)
- VCMR: Vanderbilt Cryopreserved Mouse Repository
Mouse Information
| Common Name | Slc3a1/Tyr -/- |
|---|---|
| VCMR ID | ABV |
| Date Cryopreserved | 2020-12-08 |
| Method of Cryopreservation | Sperm |
| Trial IVF % Fertilization | 81.97% |
Genetic Alteration
| Mutation #1: Nuclease-Mediated | |||
|---|---|---|---|
| Allele |
Name: solute carrier family 3, member 1 Symbol: Slc3a1em1 |
||
| Zygosity at cryopreservation | Homozygous |
||
| PCR Genotyping Protocol | Wilson_Slc3A1_Genotyping_Protocol.pdf | ||
| Citations |
|
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Background Strain Information
| Strain Type | Congenic Strain |
|---|---|
| Chimera/Founder Genetic Background | C57BL/6NHsd |
| Cryopreservation Strain Background (VCMR) | C57BL/6NHsd |
| Viability and Fertility Data | These mice are viable as both heterozygotes and homozygotes. Litter sizes can be small (2-3) to moderate (7-9) in size with larger litter sizes very uncommon. Fertility has been noted to be difficult at times usually during lower humidity winter months, but tends to rebound during more humid months. |
