James G. Patton, Ph.D.
Stevenson Professor of Biological Sciences
Director, Interdisciplinary Graduate Program
Director, MS Program in Biomedical Sciences

Record History
Added on October 22, 2020 at 1:59 PM by Uttz, Pam
Modified on March 18, 2021 at 3:38 PM by Uttz, Pam
Shared with (contributions)
Public: SPRING Meeting

Meeting Details

Start Date / Time March 24, 2021 at 9:00 AM
End Date / Time March 24, 2021 at 10:00 AM
Duration 1 hour(s)
Location Zoom
Presenter Name James G. Patton, Ph.D.
Presentation Title “Activators of Müller Glia During Retina Regeneration”
Status This meeting has already occurred

Meeting Agenda/Notes

Zebrafish are able to regenerate a variety of damaged tissues including fins, hearts, spinal cords and retinas.  In the retina, Müller glia (MG) play a key role in regeneration serving as adult stem cells capable of dedifferentiation, asymmetric division, and the generation of proliferating neuronal progenitor cells that are able to replace any lost cell type.  While the retina is highly conserved between zebrafish and humans (including MG), retina regeneration is blocked in higher vertebrates.  We seek to identify factors that can activate regeneration in fish with the aim to apply lessons learned to mammalian retina regeneration.  This talk will focus on recent work identifying activators of regeneration and testing mechanisms to deliver these activators to MG after intravitreal injection.


Document SPRING_Meeting_03.24.2021_Patton.pdf - Added on March 18, 2021 at 3:37 PM by Pam Uttz