Won Jae Huh, M.D., Ph.D.
Assistant Professor of Pathology, Microbiology & Immunology (Coffey Lab)

Jimin Min, Ph.D.
Research Fellow (Choi Lab)


Record History
Added on October 22, 2020 at 12:59 PM by Uttz, Pam
Modified on March 18, 2021 at 3:32 PM by Uttz, Pam
Shared with (contributions)
Public: SPRING Meeting

Meeting Details

Start Date / Time February 24, 2021 at 9:00 AM
End Date / Time February 24, 2021 at 10:00 AM
Duration 1 hour(s)
Location Zoom
Presenter Name Jimin Min, Ph.D.
Presentation Title Plasticity of CD133+CD166+CD44- dysplastic stem cells drives transition of dysplasia to gastric cancer
Status This meeting has already occurred

Meeting Agenda/Notes

Gastric cancer usually develops within a cascade of pre-cancerous metaplasia to cancerous dysplasia and adenocarcinoma and oncogenic Kras amplification and overexpression are associated with gastric carcinogenesis.  The dysplastic stage is especially considered a key transition state between pre-cancer and cancer, however the cellular plasticity or tumorigenic potential of the dysplastic cell lineages remain largely unknown.  Our group has recently identified dysplastic stem cell populations in active-Kras driven mouse dysplasia and this study is to investigate functional roles of the dysplastic stem cells during the cancer transition.

Attachment

Document SPRING_Meeting_02.24.2021.pdf - Added on March 18, 2021 at 3:25 PM by Pam Uttz