Holger Russ, Ph.D.
Assistant Professor 
University of Colorado​ Anschutz Medical Campus
Barbara Davis Center for Diabetes
Keywords: vcscb seminar

Record History
Added on January 9, 2020 at 12:13 PM by Uttz, Pam
Modified on January 9, 2020 at 12:14 PM by Uttz, Pam
Shared with (contributions)
Public: PDB / VCSCB Seminar - CDB Seminar Series

Meeting Details

Start Date / Time January 13, 2020 at 12:15 PM
End Date / Time January 13, 2020 at 1:15 PM
Duration 1 hour(s)
Location 1220 MRB III
Presenter Name Holger Russ, Ph.D.
Presentation Title Stem Cell derived pancreatic beta cells and thymic depithelium for basic research and cell therapy
Status This meeting has already occurred

Meeting Agenda/Notes

In this seminar I will discuss my labs efforts in generating functional cells of two endodermal derived tissues, the pancreas and the thymus, from human pluripotent stem cells for basic research and cell replacement therapy. We use these approaches and primary tissues in conjugation with genome engineering technologies to investigate biological question important for a better understanding of diabetes development in a strictly human context. Specifically, our recent results suggest that functional stem cell derived insulin-producing cells present as discrete, heterogenous cell populations and “most mature” beta-like cells can be identified and isolated using a surface marker. In addition, I discuss experimental evidence for the generation of patient specific thymic cells that are similar to cells present in human primary neonatal thymi.



Document Holger_Russ_1.13.2020.pdf - Added on January 9, 2020 at 12:13 PM by Pam Uttz