JP Cartailler, Ph.D., Director, Creative Data Solutions
Leesa Sampson, Ph.D., Senior Staff Scientist, VGER

 


Record History
Added on September 26, 2019 at 1:03 PM by Uttz, Pam
Modified on January 15, 2021 at 1:43 PM by Uttz, Pam
Shared with (contributions)
Public: SPRING Meeting

Meeting Details

Start Date / Time February 12, 2020 at 9:00 AM
End Date / Time February 12, 2020 at 10:00 AM
Duration 1 hour(s)
Location 9455 MRB IV
Presenter Name JP Cartailler, Ph.D. and Leesa Sampson , Ph.D.
Presentation Title See below
Status This meeting has already occurred

Meeting Agenda/Notes

Creative Data Solutions

The overall mission of Creative Data Solutions (CDS) is to provide bioinformatics and informatics services, and to increase the ability of investigators to both publish their work and acquire funding. Dr. Cartailler will provide an overview of the services CDS provides that are relevant to investigations in stem and progenitor cell biology. This includes the analysis of single‐cell and bulk RNA sequencing data, ChIP sequencing data, and general bioinformatics.

Vanderbilt Genome Editing Resource

Cre-lox is widely used to perform conditional gene deletions in mice but it has limitations. Dr. Sampson will describe progress to use dCas9-KRAB to conditionally suppress gene expression in mice.  By using sgRNA expressing mice, made using piggyBac, with established dCas9-KRAB repressor mice, it may be possible to achieve single and multigene knock-downs in a manner that is faster and less costly than Cre-lox.

Attachment

Document Spring_2020_Email_Notice_Cartailler_Sampson.pdf - Added on February 11, 2020 at 12:10 PM by Pam Uttz