Ethan Lippmann, Ph.D.
Assistant Professor of Chemical and Biomolecular Engineering


Record History
Added on January 4, 2018 at 1:27 PM by Uttz, Pam
Modified on April 12, 2018 at 2:10 PM by Uttz, Pam
Shared with (contributions)
Public: SPRING Meeting

Meeting Details

Start Date / Time April 18, 2018 at 9:00 AM
End Date / Time April 18, 2018 at 10:00 AM
Duration 1 hour(s)
Location 9455MRB IV
Presenter Name Ethan Lippmann, Ph.D.
Presentation Title Neurovascular modeling and biological discovery with human iPSCs
Status This meeting has already occurred

Meeting Agenda/Notes

Human blood-brain barrier (BBB) models are highly desirable for applications in drug discovery and disease modeling but have historically been limited by a lack of quality sources of brain endothelial cells. In this talk, I will detail my group's ongoing efforts to create a human BBB model from induced pluripotent stem cells (iPSCs) that faithfully represents the qualities of the BBB in vivo. I will also provide examples for how we are using our differentiation schemes to determine the molecular underpinnings of BBB function and how we are incorporating iPSC-derived brain endothelial cells into engineered tissue constructs to create more complex human neurovascular models.


Document Spring_2018_Email_Notice_Lippmann.pdf - Added on April 12, 2018 at 2:10 PM by Pam Uttz