Lauren Woodard, Ph.D.
Research Instructor
Division of Nephrology & Hypertension

Keywords: vcscb SPRING seminar

Record History
Added on January 4, 2018 at 1:11 PM by Uttz, Pam
Modified on January 19, 2018 at 10:39 AM by Uttz, Pam
Shared with (contributions)
Public: SPRING Meeting

Meeting Details

Start Date / Time January 24, 2018 at 9:00 AM
End Date / Time January 24, 2018 at 10:00 AM
Duration 1 hour(s)
Location 9455 MRB IV
Presenter Name Lauren Woodard, Ph.D.
Presentation Title Regenerating the kidney via transposon-based reprogramming to induced nephron progenitors
Status This meeting is currently scheduled

Meeting Agenda/Notes

Less than half of patients with acute kidney injury survive 90 days. In part this is because the adult mammalian kidney cannot make new nephrons, however, embryonic nephron progenitors are capable of forming all parts of the nephron. Direct reprogramming to an induced nephron progenitor state from human tubule cells will be described, including our inducible piggyBac transposon reprogramming strategy and dereplication of the transcription factors required (SIX1, EYA1, and SNAI2).