|Start Date / Time||October 26, 2016 at 9:00 AM|
|End Date / Time||October 26, 2016 at 9:55 AM|
|Location||512 Light Hall|
|Presenter Name||Joseph Elsakr (Gannon (lab)|
|Presentation Title||“The Effects of In Utero High Fat Diet Exposure on the Endocrine Pancreas of the Offspring”|
|Status||This meeting has already occurred|
The Developmental Origins of Health and Disease Hypothesis states that the gestational environment influences adult disease risk and plays a role in disease etiology. Epidemiological studies have shown that maternal overnutrition increases the offspring's risk of metabolic disease later in life. My project aims to build on a foundation of studies describing how maternal diet influences the endocrine pancreas of the offspring. Specifically, I use both mouse and non-human primate models to investigate the effects of maternal high fat diet on islet cell distribution, mass, and function, as well as epigenetic changes that may play a role in disease susceptibility.