Sarah Short, Ph.D.
Postdoctoral Fellow
Chris Williams Lab

Record History
Added on January 5, 2016 at 12:17 PM by Uttz, Pam
Modified on March 18, 2016 at 3:33 PM by Uttz, Pam
Shared with (contributions)
Public: SPRING Meeting

Meeting Details

Start Date / Time March 23, 2016 at 9:00 AM
End Date / Time March 23, 2016 at 10:00 AM
Duration 1 hour(s)
Location 9455 MRB IV
Presenter Name Sarah Short, Ph.D.
Presentation Title MTGR1 regulates stem cell function and differentiation in the intestine
Status This meeting has already occurred

Meeting Agenda/Notes

The Myeloid Translocation Gene (MTG) family are transcriptional co-repressors known to regulate stem cell function and differentiation in hematopoiesis, however little is currently known about these proteins in other tissue types. We have observed one MTG family member, MTGR1, regulates stem cell and secretory cell populations in the intestine by interfering with both Wnt and Notch signal activation. Using a variety of in vivo and ex vivo models, our current research is focused on the functional impact of MTGR1 in stem cell regulation as it pertains to intestinal injury and disease.