Current and ongoing beta cell research is presented in this weekly seminar by faculty, postdoctoral fellows and students. If you are interested in attending the Beta Cell Interest Group (BIG) seminars and joining the BIG community, please contact David Jacobson.


Record History
Added on October 22, 2015 at 3:07 PM by Brown, Deborah
Modified on February 9, 2016 at 1:42 PM by Brown, Deborah
Shared with (contributions)
BIG: Beta Cell Interest Group (BIG) seminar Master

Meeting Details

Start Date / Time February 17, 2016 at 9:00 AM
End Date / Time February 17, 2016 at 9:55 AM
Duration 55 minutes
Location 512 Light Hall
Presenter Name Peter Kropp (Maureen Gannon's lab)
Presentation Title Cooperative activity of Pdx1 and Oc1 within the pancreatic progenitors establishes competency for beta cell function
Status This meeting has already occurred

Meeting Agenda/Notes

We have discovered a dosage-dependent and cooperative role of Pdx1 and Oc1 in specification of the endocrine lineage. Heterozygosity for both Pdx1 and Oc1 results in a reduction in the number of hormone-positive cells during development and subsequent impairment in beta-cell function postnatally.