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Current and ongoing beta cell research is presented in this weekly seminar by faculty, postdoctoral fellows and students. If you are interested in attending the Beta Cell Interest Group (BIG) seminars and joining the BIG community, please contact David Jacobson.
|Start Date / Time||February 17, 2016 at 9:00 AM|
|End Date / Time||February 17, 2016 at 9:55 AM|
|Location||512 Light Hall|
|Presenter Name||Peter Kropp (Maureen Gannon's lab)|
|Presentation Title||Cooperative activity of Pdx1 and Oc1 within the pancreatic progenitors establishes competency for beta cell function|
|Status||This meeting has already occurred|
We have discovered a dosage-dependent and cooperative role of Pdx1 and Oc1 in specification of the endocrine lineage. Heterozygosity for both Pdx1 and Oc1 results in a reduction in the number of hormone-positive cells during development and subsequent impairment in beta-cell function postnatally.
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Released July 13, 2020