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SPRING Meeting

Yu-Ping Yang, Ph.D.
Research Instructor
Coffee Lay

Record History
Added on September 15, 2015 at 1:02 PM by Uttz, Pam
Modified on October 20, 2015 at 11:21 AM by Uttz, Pam
Shared with (contributions)
Public: SPRING Meeting

Meeting Details

Start Date / Time October 21, 2015 at 9:00 AM
End Date / Time October 21, 2015 at 10:00 AM
Duration 1 hour(s)
Location 9455 MRB IV
Presenter Name Yu-Ping Yang, Ph.D.
Presentation Title Generation and characterization of a novel EGFR reporter mouse
Status This meeting has already occurred

Meeting Agenda/Notes

Dysregulation of EGFR signaling has been linked in many tumor models, and several therapeutic approaches are targeted at EGFR signaling inhibition.  Although EGFR signaling is crucial in homeostasis and involved in many cellular responses , there is no reliable EGFR antibody to visualize its intracellular trafficking and dynamics in the mouse.  We recently generated an EGFR reporter mouse via CRISPR/Cas9, and I will present our characterization regarding its expression in normal condition and upon stimulation.