Kidney Services

Record History
Added on October 7, 2014 at 3:13 PM by Tripp, Fran
Modified on October 8, 2014 at 10:15 AM by Tripp, Fran
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MMPC: Cardiovascular Pathophysiology & Complications Core List of Services Master

Blood glucose levels over 72 hours can be monitored in conscious mice using Medtronic MiniMed CGMS System (Medtronic). In this system, blood glucose level is determined based on glucose concentration in interstitial fluid. A correlation between glucose levels in the blood and interstitial fluid in mice has been previously demonstrated. A fiber probe will be implanted subcutaneously.

This probe will detect interstitial glucose levels every ten seconds over three days and the signals will be stored in a glucose monitor. The probe will be removed after the experiment and the mice can be sent back to the researcher.