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|Start Date / Time||March 20, 2013 at 9:00 AM|
|End Date / Time||March 20, 2013 at 10:00 AM|
|Location||512 Light Hall|
|Presenter Name||Alessandro Ustione (Piston lab)|
|Presentation Title||“Studying the signaling of dopamine receptor D3 in the pancreatic β-cell”|
|Status||This meeting has already occurred|
Dopamine functions as a paracrine/autocrine signal in the pancreatic islets, producing a tonic inhibition of glucose-stimulated insulin secretion. The dopamine receptor D3 is expressed in the islets, and its activation changes the intracellular calcium activity in the β-cell. In this talk I discuss the experiments designed to investigate the molecular mechanisms by which the dopamine receptor D3 causes these changes.