Current and ongoing beta cell research is presented in this weekly seminar by faculty, postdoctoral fellows and students. If you are interested in attending the Beta Cell Interest Group (BIG) seminars and joining the BIG community, please contact David Jacobson.


Record History
Added on October 4, 2012 at 3:18 PM by Brown, Deborah
Modified on May 2, 2013 at 10:30 AM by Brown, Deborah
Shared with (contributions)
Public: Beta Cell Interest Group (BIG) Weekly Seminar
BIG: Beta Cell Interest Group (BIG) Weekly Seminar Master

Meeting Details

Start Date / Time May 15, 2013 at 9:00 AM
End Date / Time May 15, 2013 at 10:00 AM
Duration 1 hour(s)
Location 512 Light Hall
Presenter Name Brian McKenna (Stein lab)
Presentation Title The identification and characterization of Pdx1 co-regulators
Status This meeting has already occurred

Meeting Agenda/Notes

The transcription factor Pdx1 makes critical contributions to the identity and proliferative capacity of newly forming b-cells. Using the RE-CLIP co-immunoprecipitation technique coupled with mass spectrometry, we have identified a substantial number of novel Pdx1-interacting factors with a wide range of cellular functions. My presentation will focus on Pdx1s interaction with the Swi/Snf complex, which utilizes the energy generated from ATP-hydrolysis to mobilize histones and modulate transcription.