Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis. Albaugh VL, Judson JG, She P, Lang CH, Maresca KP, Joyal JL, Lynch CJ (2011) Mol Psychiatry 16: 569-81 Inflammatory markers and incident heart failure risk in older adults: the Health ABC (Health, Aging, and Body Composition) study. Kalogeropoulos A, Georgiopoulou V, Psaty BM, Rodondi N, Smith AL, Harrison DG, Liu Y, Hoffmann U, Bauer DC, Newman AB, Kritchevsky SB, Harris TB, Butler J, Health ABC Study Investigators (2010) J Am Coll Cardiol 55: 2129-37 Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Nass R, Pezzoli SS, Oliveri MC, Patrie JT, Harrell FE, Clasey JL, Heymsfield SB, Bach MA, Vance ML, Thorner MO (2008) Ann Intern Med 149: 601-11 Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity. Geibel M, Badurek S, Horn JM, Vatanashevanopakorn C, Koudelka J, Wunderlich CM, Brönneke HS, Wunderlich FT, Minichiello L (2014) Nat Commun 5: 3427 Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling. Boucher J, Mori MA, Lee KY, Smyth G, Liew CW, Macotela Y, Rourk M, Bluher M, Russell SJ, Kahn CR (2012) Nat Commun 3: 902 Melanocortin-3 receptor regulates the normal fasting response. Renquist BJ, Murphy JG, Larson EA, Olsen D, Klein RF, Ellacott KL, Cone RD (2012) Proc Natl Acad Sci U S A 109: E1489-98 Circadian clock gene Bmal1 is not essential; functional replacement with its paralog, Bmal2. Shi S, Hida A, McGuinness OP, Wasserman DH, Yamazaki S, Johnson CH (2010) Curr Biol 20: 316-21 Increased muscle protein breakdown in chronic hemodialysis patients with type 2 diabetes mellitus. Pupim LB, Flakoll PJ, Majchrzak KM, Aftab Guy DL, Stenvinkel P, Ikizler TA (2005) Kidney Int 68: 1857-65 Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin. Begg DP, May AA, Mul JD, Liu M, D'Alessio DA, Seeley RJ, Woods SC (2015) Diabetes 64: 2457-66 Chronic treatment with sildenafil improves energy balance and insulin action in high fat-fed conscious mice. Ayala JE, Bracy DP, Julien BM, Rottman JN, Fueger PT, Wasserman DH (2007) Diabetes 56: 1025-33 Weight cycling increases T-cell accumulation in adipose tissue and impairs systemic glucose tolerance. Anderson EK, Gutierrez DA, Kennedy A, Hasty AH (2013) Diabetes 62: 3180-8 Chronic Angiotensin-(1-7) Improves Insulin Sensitivity in High-Fat Fed Mice Independent of Blood Pressure. Williams IM, Otero YF, Bracy DP, Wasserman DH, Biaggioni I, Arnold AC (2016) Hypertension 67: 983-91 Evaluation of magnetic resonance imaging for quantification of intraabdominal fat in human beings by spin-echo and inversion-recovery protocols. Terry JG, Hinson WH, Evans GW, Schreiner PJ, Hagaman AP, Crouse JR (1995) Am J Clin Nutr 62: 297-301 Nutrient balance and energy expenditure during ad libitum feeding of high-fat and high-carbohydrate diets in humans. Thomas CD, Peters JC, Reed GW, Abumrad NN, Sun M, Hill JO (1992) Am J Clin Nutr 55: 934-42 Protein turnover and energy expenditure increase during exogenous nutrient availability in sickle cell disease. Borel MJ, Buchowski MS, Turner EA, Goldstein RE, Flakoll PJ (1998) Am J Clin Nutr 68: 607-14 Effects of resistance training with and without caloric restriction on physical function and mobility in overweight and obese older adults: a randomized controlled trial. Nicklas BJ, Chmelo E, Delbono O, Carr JJ, Lyles MF, Marsh AP (2015) Am J Clin Nutr 101: 991-9 Effect of exercise intensity on abdominal fat loss during calorie restriction in overweight and obese postmenopausal women: a randomized, controlled trial. Nicklas BJ, Wang X, You T, Lyles MF, Demons J, Easter L, Berry MJ, Lenchik L, Carr JJ (2009) Am J Clin Nutr 89: 1043-52 Longitudinal study of nutritional status, body composition, and physical function in hemodialysis patients. Johansen KL, Kaysen GA, Young BS, Hung AM, da Silva M, Chertow GM (2003) Am J Clin Nutr 77: 842-6 Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice. Luo P, Dematteo A, Wang Z, Zhu L, Wang A, Kim HS, Pozzi A, Stafford JM, Luther JM (2013) Diabetologia 56: 901-10 A potential role for insulin resistance in experimental pulmonary hypertension. West J, Niswender KD, Johnson JA, Pugh ME, Gleaves L, Fessel JP, Hemnes AR (2013) Eur Respir J 41: 861-71 Improvement in nutritional parameters after initiation of chronic hemodialysis. Pupim LB, Kent P, Caglar K, Shyr Y, Hakim RM, Ikizler TA (2002) Am J Kidney Dis 40: 143-51 Dietary supplementation of omega-3 fatty acid-containing fish oil suppresses F2-isoprostanes but enhances inflammatory cytokine response in a mouse model of ovalbumin-induced allergic lung inflammation. Yin H, Liu W, Goleniewska K, Porter NA, Morrow JD, Peebles RS (2009) Free Radic Biol Med 47: 622-8 Energy expenditure in obese children with pseudohypoparathyroidism type 1a. Shoemaker AH, Lomenick JP, Saville BR, Wang W, Buchowski MS, Cone RD (2013) Int J Obes (Lond) 37: 1147-53 Body mass index at various ages and mortality in Chinese women: impact of potential methodological biases. Zhang X, Shu XO, Chow WH, Yang G, Li H, Gao J, Gao YT, Zheng W (2008) Int J Obes (Lond) 32: 1130-6 Associations of body size and body composition with functional ability and quality of life in hemodialysis patients. Martinson M, Ikizler TA, Morrell G, Wei G, Almeida N, Marcus RL, Filipowicz R, Greene TH, Beddhu S (2014) Clin J Am Soc Nephrol 9: 1082-90 Effect of adiposity and fat distribution on endometrial cancer risk in Shanghai women. Xu WH, Matthews CE, Xiang YB, Zheng W, Ruan ZX, Cheng JR, Gao YT, Shu XO (2005) Am J Epidemiol 161: 939-47 Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome. Bingham NC, Anderson KK, Reuter AL, Stallings NR, Parker KL (2008) Endocrinology 149: 2138-48 Macrophage-derived apolipoprotein E ameliorates dyslipidemia and atherosclerosis in obese apolipoprotein E-deficient mice. Atkinson RD, Coenen KR, Plummer MR, Gruen ML, Hasty AH (2008) Am J Physiol Endocrinol Metab 294: E284-90 Monoclonal antibody antagonists of hypothalamic FGFR1 cause potent but reversible hypophagia and weight loss in rodents and monkeys. Sun HD, Malabunga M, Tonra JR, DiRenzo R, Carrick FE, Zheng H, Berthoud HR, McGuinness OP, Shen J, Bohlen P, Leibel RL, Kussie P (2007) Am J Physiol Endocrinol Metab 292: E964-76 Pericardial fat loss in postmenopausal women under conditions of equal energy deficit. Brinkley TE, Ding J, Carr JJ, Nicklas BJ (2011) Med Sci Sports Exerc 43: 808-14 Imaging methods for analyzing body composition in human obesity and cardiometabolic disease. Seabolt LA, Welch EB, Silver HJ (2015) Ann N Y Acad Sci 1353: 41-59 Association of Muscle Endurance, Fatigability, and Strength With Functional Limitation and Mortality in the Health Aging and Body Composition Study. Roshanravan B, Patel KV, Fried LF, Robinson-Cohen C, de Boer IH, Harris T, Murphy RA, Satterfield S, Goodpaster BH, Shlipak M, Newman AB, Kestenbaum B, Health ABC study (2017) J Gerontol A Biol Sci Med Sci 72: 284-291 Resistance training and pioglitazone lead to improvements in muscle power during voluntary weight loss in older adults. Marsh AP, Shea MK, Vance Locke RM, Miller ME, Isom S, Miller GD, Nicklas BJ, Lyles MF, Carr JJ, Kritchevsky SB (2013) J Gerontol A Biol Sci Med Sci 68: 828-36 Aging, resting metabolic rate, and oxidative damage: results from the Louisiana Healthy Aging Study. Frisard MI, Broussard A, Davies SS, Roberts LJ, Rood J, de Jonge L, Fang X, Jazwinski SM, Deutsch WA, Ravussin E, Louisiana Healthy Aging Study (2007) J Gerontol A Biol Sci Med Sci 62: 752-9 Pericardial fat is associated with carotid stiffness in the Multi-Ethnic Study of Atherosclerosis. Brinkley TE, Hsu FC, Carr JJ, Hundley WG, Bluemke DA, Polak JF, Ding J (2011) Nutr Metab Cardiovasc Dis 21: 332-8 Body composition and energy metabolism following Roux-en-Y gastric bypass surgery. Tamboli RA, Hossain HA, Marks PA, Eckhauser AW, Rathmacher JA, Phillips SE, Buchowski MS, Chen KY, Abumrad NN (2010) Obesity (Silver Spring) 18: 1718-24 The effect of pioglitazone and resistance training on body composition in older men and women undergoing hypocaloric weight loss. Shea MK, Nicklas BJ, Marsh AP, Houston DK, Miller GD, Isom S, Miller ME, Carr JJ, Lyles MF, Harris TB, Kritchevsky SB (2011) Obesity (Silver Spring) 19: 1636-46 Metabolic adaptation following massive weight loss is related to the degree of energy imbalance and changes in circulating leptin. Knuth ND, Johannsen DL, Tamboli RA, Marks-Shulman PA, Huizenga R, Chen KY, Abumrad NN, Ravussin E, Hall KD (2014) Obesity (Silver Spring) 22: 2563-9 Self-monitoring of spontaneous physical activity and sedentary behavior to prevent weight regain in older adults. Nicklas BJ, Gaukstern JE, Beavers KM, Newman JC, Leng X, Rejeski WJ (2014) Obesity (Silver Spring) 22: 1406-12 Childbearing may increase visceral adipose tissue independent of overall increase in body fat. Gunderson EP, Sternfeld B, Wellons MF, Whitmer RA, Chiang V, Quesenberry CP, Lewis CE, Sidney S (2008) Obesity (Silver Spring) 16: 1078-84
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.