Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor.

Chen JK, Wang DW, Falck JR, Capdevila J, Harris RC
J Biol Chem. 1999 274 (8): 4764-9

PMID: 9988714 · DOI:10.1074/jbc.274.8.4764

MeSH Terms (11)

8,11,14-Eicosatrienoic Acid Animals Cytochrome P-450 Enzyme System Epidermal Growth Factor LLC-PK1 Cells Mitogens Oxygenases Phosphorylation Second Messenger Systems Swine Transfection

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