Addition of a missense mutation present in the L gene of respiratory syncytial virus (RSV) cpts530/1030 to RSV vaccine candidate cpts248/404 increases its attenuation and temperature sensitivity.

Whitehead SS, Firestone CY, Karron RA, Crowe JE, Elkins WR, Collins PL, Murphy BR
J Virol. 1999 73 (2): 871-7

PMID: 9882287 · PMCID: PMC103906 · DOI:10.1128/JVI.73.2.871-877.1999

MeSH Terms (21)

Animals Child, Preschool Chlorocebus aethiops Double-Blind Method HN Protein Humans Infant Mice Mice, Inbred BALB C Mutation, Missense Pan troglodytes Respiratory Syncytial Virus, Human Sequence Analysis, DNA Temperature Tumor Cells, Cultured Vaccines, Attenuated Vero Cells Viral Envelope Proteins Viral Proteins Viral Vaccines Virus Replication

Connections (1)

This publication is referenced by other Labnodes entities:

Links