A conserved threonine in the second extracellular loop of the human EP2 and EP4 receptors is required for ligand binding.

Stillman BA, Audoly L, Breyer RM
Eur J Pharmacol. 1998 357 (1): 73-82

PMID: 9788776 · DOI:10.1016/s0014-2999(98)00522-6

MeSH Terms (14)

Amino Acid Substitution Binding Sites Cells, Cultured Dinoprostone Fluorescent Antibody Technique Humans Ligands Membrane Proteins Mutation, Missense Receptors, Prostaglandin E Receptors, Prostaglandin E, EP2 Subtype Receptors, Prostaglandin E, EP4 Subtype Threonine Transfection

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