A mutant yeast topoisomerase II (top2G437S) with differential sensitivity to anticancer drugs in the presence and absence of ATP.

Sabourin M, Byl JA, Hannah SE, Nitiss JL, Osheroff N
J Biol Chem. 1998 273 (44): 29086-92

PMID: 9786915 · DOI:10.1074/jbc.273.44.29086

MeSH Terms (9)

Adenosine Triphosphate Antineoplastic Agents DNA Topoisomerases, Type II Drug Resistance, Neoplasm Enzyme Stability Glycine Mutagenesis Saccharomyces cerevisiae Serine

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