Demonstration of exosite I-dependent interactions of thrombin with human factor V and factor Va involving the factor Va heavy chain: analysis by affinity chromatography employing a novel method for active-site-selective immobilization of serine proteinases.

Dharmawardana KR, Bock PE
Biochemistry. 1998 37 (38): 13143-52

PMID: 9748321 · DOI:10.1021/bi9812165

MeSH Terms (13)

Binding Sites Chromatography, Affinity Enzymes, Immobilized Factor V Factor Va Hirudins Humans Hydrolysis Peptide Fragments Sepharose Serine Endopeptidases Substrate Specificity Thrombin

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