Publication

High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol.

Barker EL, Perlman MA, Adkins EM, Houlihan WJ, Pristupa ZB, Niznik HB, Blakely RD
J Biol Chem. 1998 273 (31): 19459-68

PMID: 9677366 · DOI:10.1074/jbc.273.31.19459

MeSH Terms (23)

Animals Binding, Competitive Binding Sites Biological Transport Carrier Proteins Citalopram Drosophila Drosophila Proteins HeLa Cells Humans Mazindol Membrane Glycoproteins Membrane Proteins Membrane Transport Proteins Models, Molecular Molecular Structure Mutagenesis, Site-Directed Nerve Tissue Proteins Recombinant Fusion Proteins Serotonin Serotonin Antagonists Serotonin Plasma Membrane Transport Proteins Transfection

Connections (2)

This publication is referenced by other Labnodes entities:

Links