Limb development: molecular dysmorphology is at hand!

Innis JW, Mortlock DP
Clin Genet. 1998 53 (5): 337-48

PMID: 9660051 · DOI:10.1111/j.1399-0004.1998.tb02744.x

We present a review of limb development integrating current molecular information and selected genetic disorders to illustrate the advances made in this field over the last few years. With this knowledge, clinical geneticists can now begin to consider molecular mechanisms and pathways when investigating patients with limb malformation syndromes.

MeSH Terms (10)

Animals Bone Development Extremities Foot Deformities, Congenital Gene Expression Regulation, Developmental Genes Hand Deformities, Congenital Humans Mice Mice, Knockout

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