The transcription factor NF-ATc is essential for cardiac valve formation.

Ranger AM, Grusby MJ, Hodge MR, Gravallese EM, de la Brousse FC, Hoey T, Mickanin C, Baldwin HS, Glimcher LH
Nature. 1998 392 (6672): 186-90

PMID: 9515964 · DOI:10.1038/32426

MeSH Terms (12)

Animals Calcineurin DNA-Binding Proteins Endothelium, Vascular Gene Targeting Heart Valves Mice Morphogenesis NFATC Transcription Factors Nuclear Proteins Signal Transduction Transcription Factors

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