The bis(naphthalimide) DMP-840 causes cytotoxicity by its action against eukaryotic topoisomerase II.

Nitiss JL, Zhou J, Rose A, Hsiung Y, Gale KC, Osheroff N
Biochemistry. 1998 37 (9): 3078-85

PMID: 9485461 · DOI:10.1021/bi9723257

MeSH Terms (12)

Adenine Alleles Antineoplastic Agents DNA Topoisomerases, Type II Drug Resistance, Microbial Humans Imides Isoquinolines Mesylates Naphthalimides Organophosphonates Saccharomyces cerevisiae

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