Metabolic activation of aromatic amine mutagens by simultaneous expression of human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and N-acetyltransferase in Escherichia coli.

Josephy PD, Evans DH, Parikh A, Guengerich FP
Chem Res Toxicol. 1998 11 (1): 70-4

PMID: 9477228 · DOI:10.1021/tx970171q

MeSH Terms (10)

Arylamine N-Acetyltransferase Biotransformation Cytochrome P-450 CYP1A2 Escherichia coli Humans Hydrocarbons, Aromatic Mutagens NADH, NADPH Oxidoreductases NADPH-Ferrihemoprotein Reductase Plasmids

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