Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples.

Yamazaki H, Inoue K, Shaw PM, Checovich WJ, Guengerich FP, Shimada T
J Pharmacol Exp Ther. 1997 283 (2): 434-42

PMID: 9353355

MeSH Terms (16)

Animals Anti-Ulcer Agents Aryl Hydrocarbon Hydroxylases Cytochrome P-450 CYP2C19 Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System Fluvoxamine Humans Hydroxylation Ketoconazole Microsomes, Liver Mixed Function Oxygenases Omeprazole Rabbits Recombinant Proteins Sulfaphenazole

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