Apical enrichment of human EGF precursor in Madin-Darby canine kidney cells involves preferential basolateral ectodomain cleavage sensitive to a metalloprotease inhibitor.

Dempsey PJ, Meise KS, Yoshitake Y, Nishikawa K, Coffey RJ
J Cell Biol. 1997 138 (4): 747-58

PMID: 9265643 · PMCID: PMC2138042 · DOI:10.1083/jcb.138.4.747

MeSH Terms (19)

Animals Biological Transport Cell Line Cell Membrane Cell Polarity Dogs Epidermal Growth Factor Extracellular Space Humans Hydrolysis Kidney Metalloendopeptidases Molecular Weight Phenylalanine Protein Precursors Protein Processing, Post-Translational Protein Structure, Tertiary Solubility Thiophenes

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