A raf-independent epidermal growth factor receptor autocrine loop is necessary for Ras transformation of rat intestinal epithelial cells.

Gangarosa LM, Sizemore N, Graves-Deal R, Oldham SM, Der CJ, Coffey RJ
J Biol Chem. 1997 272 (30): 18926-31

PMID: 9228072 · DOI:10.1074/jbc.272.30.18926

MeSH Terms (18)

Animals Cell Line Cell Transformation, Neoplastic Enzyme Inhibitors ErbB Receptors Intestinal Mucosa Ligands Oncogene Protein pp60(v-src) Phosphorylation Protein Serine-Threonine Kinases Proto-Oncogene Proteins Proto-Oncogene Proteins c-raf Quinazolines ras Proteins Rats RNA, Messenger Transforming Growth Factor alpha Up-Regulation

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