The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 non-Hispanic white affected sibships.

Lindner T, Gragnoli C, Schulze J, Rietzsch H, Petzold C, Schröder HE, Cox NJ, Bell GI
Diabetes. 1997 46 (7): 1227-9

PMID: 9200660 · DOI:10.2337/diab.46.7.1227

MeSH Terms (19)

Aged ATP-Binding Cassette Transporters Base Sequence Chicago Chromosomes, Human, Pair 11 Diabetes Mellitus, Type 2 European Continental Ancestry Group Family Genetic Linkage Genetic Markers Genotype Germany Humans Middle Aged Obesity Potassium Channels Potassium Channels, Inwardly Rectifying Receptors, Drug Sulfonylurea Receptors

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