Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells.

Coffey RJ, Hawkey CJ, Damstrup L, Graves-Deal R, Daniel VC, Dempsey PJ, Chinery R, Kirkland SC, DuBois RN, Jetton TL, Morrow JD
Proc Natl Acad Sci U S A. 1997 94 (2): 657-62

PMID: 9012840 · PMCID: PMC19569 · DOI:10.1073/pnas.94.2.657

MeSH Terms (25)

Amphiregulin Cell Compartmentation Cell Nucleus Cell Polarity Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Cyclooxygenase Inhibitors EGF Family of Proteins ErbB Receptors Glycoproteins Growth Substances Humans Intercellular Signaling Peptides and Proteins Isoenzymes Membrane Proteins Mitosis Nitrobenzenes Prostaglandin-Endoperoxide Synthases Prostaglandins Pyrazoles RNA, Neoplasm Sulfonamides Sulindac Transforming Growth Factor alpha Tumor Cells, Cultured

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