Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: I. Development of an optical scanner.

Gore JC, Ranade M, MaryaƱski MJ, Schulz RJ
Phys Med Biol. 1996 41 (12): 2695-704

PMID: 8971963 · DOI:10.1088/0031-9155/41/12/009

A new method of dosimetry of ionizing radiations has been developed that makes use of tissue-equivalent polymer gels which are capable of recording three-dimensional dose distributions. The dosimetric data stored within the gels are measured using optical tomographic densitometry. The dose-response mechanism relies on the production of light scattering microparticles which result from the polymerization of acrylic comonomers dispersed in the gel. The attenuation of a collimated light beam caused by scattering in the irradiated optically turbid medium is directly related to the radiation dose over the range 0-10 Gy. An optical scanner has been developed which incorporates an He-Ne laser, photodiode detectors, and a rotating gel platform. Using mirrors mounted on a translating stage, the laser beam scans across the gel between each incremental rotation of the platform. Using the set of optical density projections obtained, a cross sectional image of the radiation field is then reconstructed. Doses in the range 0-10 Gy can be measured to better than 5% accuracy with a spatial resolution approximately 2 mm using the current prototype scanner. This method can be used for the determination of three-dimensional dose distributions in irradiated gels, including measurements of the complex distributions produced by multi-leaf collimators, dynamic wedge and stereotactic treatments, and for quality assurance procedures.

MeSH Terms (8)

Algorithms Gels Humans Models, Theoretical Phantoms, Imaging Polymers Radiation Dosage Tomography, X-Ray Computed

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