Colchicine biotransformation by human liver microsomes. Identification of CYP3A4 as the major isoform responsible for colchicine demethylation.

Tateishi T, Soucek P, Caraco Y, Guengerich FP, Wood AJ
Biochem Pharmacol. 1997 53 (1): 111-6

PMID: 8960070 · DOI:10.1016/s0006-2952(96)00693-4

MeSH Terms (6)

Colchicine Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System Gout Suppressants Humans Microsomes, Liver

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