Topoisomerase II.etoposide interactions direct the formation of drug-induced enzyme-DNA cleavage complexes.

Burden DA, Kingma PS, Froelich-Ammon SJ, Bjornsti MA, Patchan MW, Thompson RB, Osheroff N
J Biol Chem. 1996 271 (46): 29238-44

PMID: 8910583 · DOI:10.1074/jbc.271.46.29238

MeSH Terms (9)

Animals Antineoplastic Agents DNA DNA Topoisomerases, Type II Drosophila melanogaster Etoposide Hydrolysis Kinetics Protein Binding

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