Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.

Shimada T, Hayes CL, Yamazaki H, Amin S, Hecht SS, Guengerich FP, Sutter TR
Cancer Res. 1996 56 (13): 2979-84

PMID: 8674051

MeSH Terms (20)

Adult Amines Animals Biotransformation Carcinogens Catalysis Chrysenes Cytochrome P-450 Enzyme System DNA, Complementary Humans Isoenzymes Microsomes Mutagens NADPH-Ferrihemoprotein Reductase Polycyclic Compounds Prodrugs Rabbits RNA Saccharomyces cerevisiae Substrate Specificity

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