Analysis of variables affecting wound healing after musculoskeletal sarcoma resections.

Chmell MJ, Schwartz HS
J Surg Oncol. 1996 61 (3): 185-9

PMID: 8637204 · DOI:10.1002/(SICI)1096-9098(199603)61:3<185::AID-JSO4>3.0.CO;2-7

Adjuvant treatment modalities, nutritional parameters, and allogenic blood transfusions are investigated as possible contributing variables which may adversely affect wound healing after tumor resections for musculoskeletal sarcomas. Statistical analysis determined that preoperative chemotherapy, depressed preoperative hematocrit, and allogenic blood transfusions (probably immunosuppression mediated) were the only significant factors affecting wound healing outcome. Suggestions to improve postoperative infection rates are discussed.

MeSH Terms (22)

Analysis of Variance Blood Transfusion Bone Neoplasms Chemotherapy, Adjuvant Female Hematocrit Humans Immunosuppression Male Middle Aged Muscle Neoplasms Nutritional Physiological Phenomena Preoperative Care Radiotherapy, Adjuvant Retrospective Studies Sarcoma Sarcoma Soft Tissue Neoplasms Surgical Wound Dehiscence Surgical Wound Infection Treatment Outcome Wound Healing

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