Regulation of the human serotonin transporter. Cholera toxin-induced stimulation of serotonin uptake in human placental choriocarcinoma cells is accompanied by increased serotonin transporter mRNA levels and serotonin transporter-specific ligand binding.

Ramamoorthy S, Cool DR, Mahesh VB, Leibach FH, Melikian HE, Blakely RD, Ganapathy V
J Biol Chem. 1993 268 (29): 21626-31

PMID: 8408014

MeSH Terms (19)

Binding Sites Carrier Proteins Cholera Toxin Choriocarcinoma Cyclic AMP Cycloheximide Dactinomycin DNA, Complementary Female Humans Ligands Membrane Glycoproteins Membrane Transport Proteins Nerve Tissue Proteins Placenta RNA, Messenger Serotonin Serotonin Plasma Membrane Transport Proteins Tumor Cells, Cultured

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