Novel 1-8-bridged chiral quinolones with activity against topoisomerase II: stereospecificity of the eukaryotic enzyme.

Froelich-Ammon SJ, McGuirk PR, Gootz TD, Jefson MR, Osheroff N
Antimicrob Agents Chemother. 1993 37 (4): 646-51

PMID: 8388196 · PMCID: PMC187729 · DOI:10.1128/AAC.37.4.646

MeSH Terms (11)

Animals Cells, Cultured Cell Survival DNA Drosophila melanogaster Escherichia coli Eukaryotic Cells Ofloxacin Quinolones Stereoisomerism Topoisomerase II Inhibitors

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