Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes.

Thier R, Taylor JB, Pemble SE, Humphreys WG, Persmark M, Ketterer B, Guengerich FP
Proc Natl Acad Sci U S A. 1993 90 (18): 8576-80

PMID: 8378332 · PMCID: PMC47400 · DOI:10.1073/pnas.90.18.8576

MeSH Terms (22)

Animals Base Composition Base Sequence Cloning, Molecular Escherichia coli Ethylene Dibromide Ethylene Dichlorides Genetic Vectors Glutathione Transferase Humans Hydrocarbons, Halogenated Isoenzymes Molecular Sequence Data Mutagenesis Mutagens Oligodeoxyribonucleotides Plasmids Polymerase Chain Reaction Polymorphism, Genetic Rats Salmonella typhimurium Transfection

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