Sequential imputation and multipoint linkage analysis.

Kong A, Cox N, Frigge M, Irwin M
Genet Epidemiol. 1993 10 (6): 483-8

PMID: 8314048 · DOI:10.1002/gepi.1370100626

A novel Monte Carlo method for linkage analyses involving large pedigrees and many polymorphic loci is introduced. Issues related to the efficiency of the method are discussed.

MeSH Terms (7)

Chromosome Mapping Genetic Diseases, Inborn Genetic Linkage Genetic Markers Humans Monte Carlo Method Pedigree

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