p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein.

Slebos RJ, Lee MH, Plunkett BS, Kessis TD, Williams BO, Jacks T, Hedrick L, Kastan MB, Cho KR
Proc Natl Acad Sci U S A. 1994 91 (12): 5320-4

PMID: 8202487 · PMCID: PMC43986 · DOI:10.1073/pnas.91.12.5320

MeSH Terms (17)

Cell Cycle Cell Line Cyclin-Dependent Kinase Inhibitor p21 Cyclins DNA Damage Gene Expression Humans Oncogene Proteins, Viral Papillomaviridae Papillomavirus E7 Proteins Phosphorylation Proteins Repressor Proteins Retinoblastoma Protein RNA, Messenger Transfection Tumor Suppressor Protein p53

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