Inherited enhancement of hydroxyl radical generation and lipid peroxidation in the S strain rats results in DNA rearrangements, degenerative diseases, and premature aging.

Salganik RI, Solovyova NA, Dikalov SI, Grishaeva ON, Semenova LA, Popovsky AV
Biochem Biophys Res Commun. 1994 199 (2): 726-33

PMID: 8135816 · DOI:10.1006/bbrc.1994.1289

MeSH Terms (23)

Aging Animals Cataract DNA Female Fertility Genetic Predisposition to Disease Heart Hydroxyl Radical Intracellular Membranes Lipid Peroxidation Liver Longevity Lysosomes Male Mitochondria, Heart Mitochondria, Liver Myocardium Radiography Rats Rats, Mutant Strains Rats, Wistar Spinal Cord

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