A pyrimido[1,6-a]benzimidazole that enhances DNA cleavage mediated by eukaryotic topoisomerase II: a novel class of topoisomerase II-targeted drugs with cytotoxic potential.

Corbett AH, Guerry P, Pflieger P, Osheroff N
Antimicrob Agents Chemother. 1993 37 (12): 2599-605

PMID: 8109923 · PMCID: PMC192751 · DOI:10.1128/AAC.37.12.2599

MeSH Terms (11)

4-Quinolones Animals Anti-Infective Agents Benzimidazoles DNA, Bacterial DNA Topoisomerases, Type II Drosophila melanogaster Nucleic Acid Conformation Pyrimidines Pyrimidinones Stimulation, Chemical

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