Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV-infected mice.

Crowe JE, Murphy BR, Chanock RM, Williamson RA, Barbas CF, Burton DR
Proc Natl Acad Sci U S A. 1994 91 (4): 1386-90

PMID: 8108420 · PMCID: PMC43163 · DOI:10.1073/pnas.91.4.1386

MeSH Terms (15)

Administration, Intranasal Animals Antibodies, Monoclonal Antibodies, Viral Female Humans Immunization, Passive Immunoglobulin Fab Fragments Immunotherapy Lung Diseases Mice Mice, Inbred BALB C Recombinant Proteins Recurrence Respiratory Syncytial Virus Infections

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